MrBayes is a program for the Bayesian estimation of phylogeny. Bayesian inference of phylogeny is based upon a quantity called the posterior probability distribution of trees, which is the probability of a tree conditioned on the observations. The conditioning is accomplished using Bayes’s theorem. The posterior probability distribution of trees is impossible to calculate analytically; instead, MrBayes uses a simulation technique called Markov chain Monte Carlo (or MCMC) to approximate the posterior probabilities of trees.

MrBayes is available on the atlas4 and atlas5 cluster for parallel jobs.

To run a parallel job, create a script file call run_mbp with the following lines as its content:

On atlas4 cluster:
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#BSUB -o my_job.eo
#BSUB -q atlas4_parallel
#BSUB -n 16  (Note: choose the number of CPUs according to the load of the system)
mpirun  /app1/linux/MrBayes/mrbayes-3.1.2-a4/mb   input_file  >  output_file
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On atlas5 cluster:
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#BSUB -o my_job.eo
#BSUB -q 8core_parallel
#BSUB -n 16  (Note: choose the number of CPUs according to the load of the system)
mpirun  /app1/linux/MrBayes/mrbayes-3.1.2/mb   input_file  >  output_file
—————————

To submit the job:
> bsub < run_mbp

Please feedback problems to ccehpc@nus.edu.sg.